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KMID : 0370819920070010093
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Yonsei Journal Dental Science
1992 Volume.7 No. 1 p.93 ~ p.110
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THE EFFECTS OF POROUS REPLAMINEFORM HYDROXYAPATITE ON THE REGENERATION OF THE ALVEOLAR BONE IN THE PERIODONTALLY INVOLVED EXTRACTION SOCKETS IN DOGS
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Abstract
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Regeneration of the periodontal tissue destroyed by periodontal disease is one of the final goals of periodontal therapy. In the past few years, periodontists have used various alloplastic grafting materials in an attempt to regenerate bone lost
from
periodontal disease. Among these materials, porous replamineform hydroxyapatite is one of the most widely used implant material, because it has been shown to be nontoxic, biologically compatible with surrounding host tissue and chemically similar
to
bone.
The purpose of this study was to evaluate whether the effects of porous replamineform hydroxyapatite on the regeneration of the alveolar bone between fresh extraction socket and periodontally involved extraction socket are different. Experimental
periodontitis was induced by the ligation of orthodontic elastic threads after surgically creating periodontal defect on premolars of right side of 6 adult dogs for 8 weeks. thereafter, following the extraction of each teeth, porous replamineform
hydroxyapatite was inserted in extraction sockets. Control group was fresh extraction sockets with hydroxyapatite, and experimental group was periodontally involved extraction sockets with hydroxyapatite. Thereafter, dogs were sacrificed at 2, 8,
12
weeks, and the specimens were prepared and stained hematoxyin-Eosin stain for the light microscopic evaluation.
@ES The results of this study were as follow.
@EN In the aspects of the inflammtory cell infiltration in subepithelial connective tissue, control and experimental group showed moderate aggregation at 2 weeks. but, It disappeared at 8, 12 weeks in both groups.
2. Lack of inflammatory response associated with porous replamineform hydroxyapatite particle was seen at 2, 8, 12 weeks in both groups.
3. New bone was formed at socket wall and socket base from 2 weeks. At 8,12 weeks bone regeneration was more extensive than 2 weeks, most of the implanted porous hydroxyapatite particles encased in new bone while those in the coronal part of
socket
were surrounded by connective tissue. At 12 weeks lamellar bone was partly replaced. There were no differances between 2 groups.
4. In both control and experimental group, most of the implanted porous hydroxyapatite particles remained within the extraction socket, and resorption of buccal and lingual plate was not seen.
5. Multinucleated giant cells neighboring implanted porous hydroxyapatite particles were seen from 8 weeks in both groups.
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KEYWORD
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